Major Highways
- Interstate 4: 132 miles (211 km) connecting the Tampa Bay area on the west coast through Orlando to the Daytona Beach area on the east coast.
- Interstate 10: 362 (579 km) miles connecting Jacksonville on the east coast with the Alabama state line, west of Pensacola.
- Interstate 75: 417 miles (754 km) entering Florida from Georgia through Lake City to the Tampa Bay area on the west coast, south through Fort Myers and Naples where it crosses the state to Fort Lauderdale (the Naples-Fort Lauderdale segment is commonly called Alligator Alley).
- Interstate 95: 347 miles (555 km) from the Georgia line near Jacksonville, down the east coast to Miami.
- Florida Turnpike (Sunshine State Parkway): 265 miles (424 km) from its northern entrance at Wildwood to the Miami/Homestead area, this highway is sometime called Main Street Florida.
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